The CloSys is actually a revolutionary way to deliver chlorine dioxide which is not stable. Chlorine dioxide is a gentle, weak oxidant compared to other oxidants, but it is also a broad spectrum anti-microbial. It's powerful enough that it is used to disinfect anthrax. There was a bit of a scam a few years ago in getting people to ingest sodium chlorite internally (it would then turn into chlorine dioxide upon contact with an acid), called Miracle Mineral Supplement. CloSys also has unique wetting properties that make it glide under the gumline. So the main purpose of CloSys is to eradicate pathogenic bacteria from the mouth and restore and heal up gum pockets back to normal (or prevent them in the first place). No need to fuss around with annoying irrigators and other too-much-work approaches. I can tell you that the CloSys does a better job at cleaning the mouth than Listerine if going by morning-breath is any indication... it should, since it's modern chemistry compared to Listerine which is just an old herbal formula once marketed for use as a douche!WiseOne wrote: Where did you hear about this regime, or did you develop it yourself? A question...what's the extra benefit provided by the closys pre-brushing? Brushing alone + Listerine should be enough to deal with oral pathogens, but no amount of mouthwashing is going to convert your mouth into an OR clean room.
Also, the ACT brand is necessary. The Walmart clone version did not have the same level of stickiness and I don't think it was eradicating all of the Listerine as I was starting to get tooth pain. However, I've found the Walmart clone version of Listerine to be completely acceptable since its just essential oil extracts and acid in water. I love the Machiavellian irony of selling highly acidic Listerine as a last oral care step and keeping dentists in business.
I no longer advocate the use of Dr. Schulze's Tooth & Gum Formula in the regime. It causes teeth staining, unfortunately. I'd reserve its use for really serious mouth cases, which is highly unlikely to happen to anyone ever using this regime.
I've tried all the alternative approaches (baking soda, neem, peelu, xylitol, essential oils, etc.) over the years and they are just not as effective as this combined regime with chemicals. That's just how it is. Unlike Gumby, I don't have the time every day to sit around and thoroughly outline my teeth and gumline with a stick.

One last thing... I cannot take CloSys twice a day as I get a nasty metallic taste on my tongue and in mouth and it effects taste for a day or two. So, I use baking soda in water as a pre-rinse in the morning. I just don't brush with it as its too harsh and strips the protective biofilm off your teeth. No idea if a microfiber cloth strips that off, MT!