Actually, based on what you've already said, I'm fairly certain your wife has Peripheral Neuropathy. Most people with Peripheral Neuropathy report the exact symptoms you've described.
According to Wikipedia...
While Chiropractors and Physical Therapists may help ease the pain, they likely won't be able to treat the underlying problem. They are likely just treating the symptom.
Peripheral Neuropathy can be caused by a number of things, such as...
* Liver infections
* Low levels of vitamin B12
* Poisoning due to heavy metals, such as lead or mercury or solvents
* Poor blood flow to the legs
* Underactive thyroid gland
* Broken bone that affects a nerve
* Drugs that treat infections, cancer, seizures, and high blood pressure
* Pressure on a nerve, such as carpal tunnel syndrome
* Being exposed to cold temperatures for a long period of time
* Pressure from bad-fitting casts, splints, a brace, or crutches
If the problem isn't caused by a specific physical pressure on the nerves, my recommendation would be to find a "
functional medical practitioner" or a "DAN physician" (Defeat Autism Now)
who specializes in the methylation pathways (for detox). Often those with methylation issues have a number of genetic defects that require specific workarounds. One way to find such a practitioner is to contact a local compounding pharmacy near you and ask them if they know of a physician who specializes in treating methylation disorders. Usually they will know such a physician or practitioner because those kinds of physicians tend to order compounded pharmaceuticals. If that practitioner knows what they are doing, they will order a specific genetic test to determine which methylation enzymes are upregulated or downregulated — which can help them plan a course of action.
Some people have good success treating Peripheral Neuropathy with methylfolate and active forms of b12 and rAlpha Lipoic Acid (it all depends on what the underlying cause is). However, I do not recommend self-treating without the guidance of a knowledgeable physician or practitioner because it is very easy to overdose on these vitamins when methylation pathways aren't working properly.
Of course, if the problem is purely physical, it would probably be worth seeing an osteopath who is trained in functional medicine. Either way, there are very few mainstream doctors who understand how to test or treat the underlying cause.
I am not a doctor, but hopefully Benko or BareBones (or any other doctors) can chime in (MG, though not a doctor, is very knowledgeable as well).
Nothing I say should be construed as advice or expertise. I am only sharing opinions which may or may not be applicable in any given case.