The Permanent Supplement Regime

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MachineGhost
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Re: The Permanent Supplement Regime

Post by MachineGhost » Sun Jun 26, 2016 12:47 am

Very surprising! K seems severely underrated by everyone. A "high" intake would be at least the average intake of K1 (626.4 mcg/day) and K2 (57.5 mcg/day), i.e. a proper K complex supplement will be double those values (as they are).

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Dietary intake of vitamin K is inversely associated with mortality risk.

Vitamin K has been related to cardiovascular disease and cancer risk. However, data on total mortality are scarce. The aim of the present study was to assess the association between the dietary intake of different types of vitamin K and mortality in a Mediterranean population at high cardiovascular disease risk. A prospective cohort analysis was conducted in 7216 participants from the PREDIMED (Prevención con Dieta Mediterránea) study (median follow-up of 4.8 y). Energy and nutrient intakes were evaluated using a validated 137-item food frequency questionnaire. Dietary vitamin K intake was calculated annually using the USDA food composition database and other published sources. Deaths were ascertained by an end-point adjudication committee unaware of the dietary habits of participants after they had reviewed medical records and linked up to the National Death Index. Cox proportional hazard models were fitted to assess the RR of mortality. Energy-adjusted baseline dietary phylloquinone intake was inversely associated with a significantly reduced risk of cancer and all-cause mortality after controlling for potential confounders (HR: 0.54; 95% CI: 0.30, 0.96; and HR: 0.64; 95% CI: 0.45, 0.90, respectively). In longitudinal assessments, individuals who increased their intake of phylloquinone or menaquinone during follow-up had a lower risk of cancer (HR: 0.64; 95% CI: 0.43, 0.95; and HR: 0.41; 95% CI: 0.26, 0.64, respectively) and all-cause mortality (HR: 0.57; 95% CI: 0.44, 0.73; and HR: 0.55; 95% CI: 0.42, 0.73, respectively) than individuals who decreased or did not change their intake. Also, individuals who increased their intake of dietary phylloquinone had a lower risk of cardiovascular mortality risk (HR: 0.52; 95% CI: 0.31, 0.86). However, no association between changes in menaquinone intake and cardiovascular mortality was observed (HR: 0.76; 95% CI: 0.44, 1.29). An increase in dietary intake of vitamin K is associated with a reduced risk of cardiovascular, cancer, or all-cause mortality in a Mediterranean population at high cardiovascular disease risk. This trial was registered at http://www.controlled-trials.com as ISRCTN35739639.

http://www.ncbi.nlm.nih.gov/pubmed/24647393
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Maddy
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Re: The Permanent Supplement Regime

Post by Maddy » Sat Jul 09, 2016 6:15 pm

MK et al., would you comment on the idea of using kelp as a one-stop source of dietary minerals?
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MachineGhost
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Re: The Permanent Supplement Regime

Post by MachineGhost » Sat Jul 09, 2016 7:07 pm

Maddy wrote:MK et al., would you comment on the idea of using kelp as a one-stop source of dietary minerals?
Vegetables don't have much vitamins or minerals per se, i.e. not RDA levels. So I wouldn't count on it. They're only useful for phytonutrients and fiber.

They also have a nasty habit of accumulating toxic minerals like thallium. There was a story a few years ago about that and kelp. Apparantly there's a county in Northern California where people are health nuts and eat way too much kelp in smoothies every day so were devloping symptoms of thallium poisioning.

Personally, I've found my self-grown organic raw kelp to overstimulate me and give me a fatique crash the next day. Don't know if thats a sign of toxicity or there's just something stimulating in it (I'm very sensitive to stimulants though I would get a rebound headache to indeed indicate it was that afterwards). Cooked kelp seemed better but it still kept me up way past my bedtime. It wasn't a wired feeling just lack of being tired.

EDIT: Ooops, my bad! I was thinking of kale not kelp. Sea vegetables are the most concentrated source of minerals so they would work for trace minerals. However, I don't recall seeing any were ever dense enough to meet the RDA, so look into it. Kelp is essentially used for getting a naturally concentrated source of iodine.
"All generous minds have a horror of what are commonly called 'Facts'. They are the brute beasts of the intellectual domain." -- Thomas Hobbes

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Re: The Permanent Supplement Regime

Post by Maddy » Tue Aug 02, 2016 6:32 pm

MG et al., if you were limited to just a few supplements, which ones would you choose if your goal were to bring about a significant increase in energy level?
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Re: The Permanent Supplement Regime

Post by Kriegsspiel » Tue Aug 02, 2016 7:59 pm

Ephedrine.

Take a Bronkaid tablet (20mg ephedrine) and a 200mg caffeine pill and you will be wired.

Not recommended if your heart is prone to exploding.
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Re: The Permanent Supplement Regime

Post by Maddy » Tue Aug 02, 2016 8:36 pm

I wasn't exactly looking for "wired." I'd settle for feeling like 30 again.
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Re: The Permanent Supplement Regime

Post by MachineGhost » Thu Aug 04, 2016 3:10 pm

"All generous minds have a horror of what are commonly called 'Facts'. They are the brute beasts of the intellectual domain." -- Thomas Hobbes

Disclaimer: I am not a broker, dealer, investment advisor, physician, theologian or prophet.  I should not be considered as legally permitted to render such advice!
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Re: The Permanent Supplement Regime

Post by rocketdog » Wed Nov 09, 2016 8:59 am

Assuming you don't suffer from a chronic health condition, the human body does not need supplements in pill form if you eat a healthy, varied diet. That said, I take these supplements:
  • Multi-vitamin - Doctor recommended as a "safety net" just in case I'm missing anything in my vegetarian diet (unlikely).
  • Calcium - I eat very little dairy (mostly a little cheese here and there), so again, just a safety net.
  • Vitamin D3 - Doctor recommended 5000IU daily. Whatever you say, doc.
  • Low-dose aspirin - Twice weekly now that I'm over 50, for the potential protection against heart attacks, strokes, and colon cancer.
I used to also take vitamin C thinking that it warded off colds, but I eat fresh fruits and vegetables every day so I already intake a good quantity of natural vitamin C and I have not noticed an increase in illness since I stopped taking it in pill form. Leaves me with more money to invest in the Permanent Portfolio. ;)
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Re: The Permanent Supplement Regime

Post by Maddy » Fri Aug 17, 2018 2:18 pm

I tend to be pretty skeptical when it comes to alternative remedies that purport to do earth-shattering things, but after a good deal of experimenting, I have the following earth-shattering anecdote to offer about an herbal by the name of Ashwaganda root. It's touted as being an "adaptogen" which supposedly helps with stress and which has a number of other supposed attributes, including the ability to boost thyroid function.

I can't really speak to those issues, but I've found Ashwaganda to be as effective a sleep aid as Ambien. I buy the root in powdered form and fill Size 00 gelatin capsules, then take two capsules a half hour before bedtime. Now, I'm one of those people who frequently lies in bed watching the clock for four or five hours, and sometimes gets up twice during the night, before actually falling asleep. And I'm generally wrung out the next day. But since taking a dose of Ashwaganda at bedtime, I sleep like a log. I also notice that I'm a whole lot calmer during the day, something upon which a neutral third party spontaneously commented.

Maybe my experience will help some other folks here.
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Re: The Permanent Supplement Regime

Post by barrett » Sat Aug 18, 2018 6:40 am

Chronic insomniac here, Maddy. Thanks for posting that. Will report back!
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ochotona
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Re: The Permanent Supplement Regime

Post by ochotona » Sat Aug 18, 2018 7:23 am

My gastroenterologist says to take calcium, selenium, a probiotic, and a low dose aspirin. I'm at elevated risk of colon cancer.
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Re: The Permanent Supplement Regime

Post by Kriegsspiel » Sat Aug 18, 2018 11:22 am

I've been taking zinc, magnesium, B6, fish oil, and D3 before going to sleep, and I've been sleeping even more like a stone than usual, with the added bonus of insane technicolor LSD dreams.
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